Blar i Bergen Open Research Archive på forfatter "Pilskog, Sara Margareta Cecilia"

Viser treff 1-7 av 7

    • Combined RBE and OER optimization in proton therapy with FLUKA based on EF5-PET 

      Henjum, Helge; Dahle, Tordis Johnsen; Mairani, Andrea; Pilskog, Sara Margareta Cecilia; Stokkevåg, Camilla Hanquist; Boer, Camilla Grindeland; Redalen, Kathrine Røe; Minn, Heikki; Malinen, Eirik; Ytre-Hauge, Kristian Smeland (Journal article; Peer reviewed, 2023)
      Introduction Tumor hypoxia is associated with poor treatment outcome. Hypoxic regions are more radioresistant than well-oxygenated regions, as quantified by the oxygen enhancement ratio (OER). In optimization of proton ...

    • Influence of beam pruning techniques on LET and RBE in proton arc therapy 

      Henjum, Helge; Tjelta, Johannes; Fjæra, Lars Fredrik; Pilskog, Sara Margareta Cecilia; Stokkevåg, Camilla Hanquist; Lyngholm, Erlend; Handeland, Andreas Havsgård; Ytre-Hauge, Kristian Smeland (Journal article; Peer reviewed, 2023)
      Introduction: Proton arc therapy (PAT) is an emerging treatment modality that holds promise to improve target volume coverage and reduce linear energy transfer (LET) in organs at risk. We aimed to investigate if pruning ...

    • An organ deformation model using Bayesian inference to combine population and patient-specific data 

      Rørtveit, Øyvind Lunde; Hysing, Liv Bolstad; Stordal, Andreas Størksen; Pilskog, Sara Margareta Cecilia (Journal article; Peer reviewed, 2023)
      Objective. Organ deformation models have the potential to improve delivery and reduce toxicity of radiotherapy, but existing data-driven motion models are based on either patient-specific or population data. We propose to ...

    • The Organ Sparing Potential of Different Biological Optimization Strategies in Proton Therapy 

      Henjum, Helge; Dahle, Tordis Johnsen; Fjæra, Lars Fredrik; Rørvik, Eivind; Pilskog, Sara Margareta Cecilia; Stokkevåg, Camilla H.; Mairani, Andrea; Ytre-Hauge, Kristian Smeland (Journal article; Peer reviewed, 2021)
      Purpose: Variable relative biological effectiveness (RBE) models allow for differences in linear energy transfer (LET), physical dose, and tissue type to be accounted for when quantifying and optimizing the biological ...

    • Reducing systematic errors due to deformation of organs at risk in radiotherapy 

      Rørtveit, Øyvind Lunde; Hysing, Liv Bolstad; Stordal, Andreas Størksen; Pilskog, Sara Margareta Cecilia (Journal article; Peer reviewed, 2021)
      Purpose In radiotherapy (RT), the planning CT (pCT) is commonly used to plan the full RT-course. Due to organ deformation and motion, the organ shapes seen at the pCT will not be identical to their shapes during RT. Any ...

    • Reduction of PTV margins for elective pelvic lymph nodes in online adaptive radiotherapy of prostate cancer patients 

      Brennsæter, John Alfred; Dahle, Tordis Johnsen; Moi, Jannicke Nøkling; Svanberg, Ingvild Førsvoll; Haaland, Gry Sandvik; Pilskog, Sara Margareta Cecilia (Journal article; Peer reviewed, 2023)
      Background Cone beam CT (CBCT) based online adaptive radiotherapy (oART) is a new development in radiotherapy. With oART, the requirements for planning target volume (PTV) margins differ from standard therapy because ...

    • Towards range-guidance in proton therapy to detect organ motion-induced dose degradations 

      Busch, Kia; Andersen, Andreas G.; Petersen, Jørgen B.B.; Petersen, Stine E.; Rønde, Heidi S.; Bentzen, Line; Pilskog, Sara Margareta Cecilia; Skyt, Peter; Nørrevang, Ole; Muren, Ludvig Paul (Journal article; Peer reviewed, 2022)
      Introduction: Internal organ motion and deformations may cause dose degradations in proton therapy (PT) that are challenging to resolve using conventional image-guidance strategies. This study aimed to investigate the ...